Former coalition partners’ decision brings Scottish first minister to brink of losing vote, which could make his position untenable

• Explainer: what was the SNP and Greens’ deal?

Humza Yousaf could be forced to quit as Scotland’s first minister after the Scottish Greens announced they would back a motion of no confidence against him at Holyrood.

The Scottish National party’s former coalition partners declared they would vote next week against the man who had “betrayed” them, hours after he unilaterally ended their power-sharing deal.

Wang Yi says recent improvements in ties face ‘disruptions’ amid threats of sanctions over support for Russia’s defence industry

China’s foreign minister, Wang Yi, has warned the US that the recent improvements in the two countries’ relations were being jeopardised by “disruptions” which could take them back to a “downward spiral” leading to rivalry, confrontation and even conflict.

Wang was speaking at the start of a meeting in Beijing with the US secretary of state, Antony Blinken, at a time of renewed tension in the relations between the superpowers.

Gideon Falter was in running to be adviser but government’s antisemitism tsar warned against appointment

• Who are CAA, the group headed by campaigner in Met police antisemitism row?

The Home Office considered appointing campaigner against antisemitism Gideon Falter as an adviser to its counter extremism unit but was warned against the appointment by the government’s antisemitism tsar.

The Guardian understands there were strong objections to Falter being offered the part-time civil service role advising the Commission for Countering Extremism (CCE) in 2022 and that John Mann told the then home secretary Suella Braverman he would quit if Falter was offered the post.

Excitement among patients and researchers as custom-built jabs enter phase 3 trial

Doctors have begun trialling in hundreds of patients the world’s first personalised mRNA cancer vaccine for melanoma, as experts hailed its “gamechanging” potential to permanently cure cancer.

Melanoma affects about 132,000 people a year globally and is the biggest skin cancer killer. Currently, surgery is the main treatment although radiotherapy, medicines and chemotherapy are also sometimes used.

First payments to be made during an ongoing conflict is ‘important step towards restoring justice’, says first lady, Olena Zelenska

The first reparation payments are to be made in the next few weeks to survivors of wartime rape by Russian soldiers during the invasion of Ukraine, in a move that Ukraine’s first lady, Olena Zelenska, called “an important step towards restoring justice”.

Up to 500 Ukrainian survivors of conflict-related sexual violence are being identified and awarded with interim reparations this year, including financial, medical and psychological support.

Stark new projections suggest annual admissions will rise to 151,000, costing the NHS and economy £75bn

The number of people in the UK experiencing a stroke will increase more than 50% to 151,000 a year by 2035, costing the NHS and the economy £75bn in healthcare and lost productivity, stark new projections suggest.

Worsening physical health, rising alcohol consumption and low exercise levels among an ageing population as well as a failure by ministers and the health service to do more to prevent ill health are blamed for the predicted spike in strokes.

Teachers say behaviour getting worse as survey also shows parents getting less supportive of school policies

Only two in five children in England say they always feel safe at school, according to a government survey, and teachers from across Britain have told the Guardian they have seen pupils’ behaviour deteriorate over the last two years.

Teachers said violence and abuse aimed at school staff and other students had increased alongside displays of homophobia, racism and sexism, with women in particular bearing the brunt of aggressive sexual remarks.

The former president’s motion for a new trial was denied and his argument deemed ‘entirely without merit’

A federal judge on Thursday upheld the verdict and award of more than $83m to the writer E Jean Carroll in a defamation case against Donald Trump after he called her a liar for accusing him of sexually assaulting her.

Judge Lewis Kaplan, a senior district judge on the US district court for the southern district of New York, denied Trump’s motion for a new trial and affirmed that Carroll suffered harm caused by Trump’s 2019 public statements.

Ministers considering more funding to protect important research sites, with China seen as a particular concern

MI5 has warned universities that hostile foreign states are targeting sensitive research, as ministers consider measures to bolster protections.

Vice-chancellors from 24 leading institutions, including Oxford, Cambridge and Imperial College London, were briefed on the threat by the domestic security service’s director general, Ken McCallum, and National Cybersecurity Centre (NCSC) chief, Felicity Oswald.

Concern grows over legality of government’s approach as new figures show more than 150,000 carers facing huge penalties

• A hero – then sacked. The carer’s allowance whistleblower

New figures show more than 150,000 unpaid carers are now facing huge fines for minor rule breaches, as MPs, charities and campaigners demanded an immediate amnesty.

Ed Davey, the Lib Dem leader, joined calls to write off the vast debts incurred by tens of thousands of people who care for sick, disabled and elderly relatives after experts raised concerns about the legality of the government’s approach.